Eruptive xanthoma associated with severe hypertriglyceridemia and poorly controlled type 1 diabetes mellitus

J Community Hosp Intern Med Perspect. 2019 Sep 5;9(4):344-346. doi: 10.1080/20009666.2019.1650591. eCollection 2019.

Abstract

Eruptive xanthoma is characterized by yellowish skin papules encircled by an erythematous halo and associated with severe hypertriglyceridemia above 2,000 mg/dl. Hypertriglyceridemia can be caused by primary genetic mutations, secondary causes, such as uncontrolled diabetes, obesity, alcohol overuse, or combinations of both. Eruptive xanthoma can serve as an important clinical indicator of underlying systemic conditions (e.g. hypertriglyceridemia and uncontrolled diabetes mellitus). It is important for clinicians to recognize it to prevent further complications such as pancreatitis and cardiovascular disease.

Keywords: Apo B/A1 ratio; Eruptive xanthoma; cardiovascular disease; fenofibrate; hypertriglyceridemia; life style modification; pancreatitis; type 1 diabetes mellitus.

Publication types

  • Case Reports