Polypodium leucotomos is widely available as an oral supplement and has been shown to exhibit photoprotective properties which might provide adjunctive benefit when used along with topically applied suncreens. However, data are lacking with the majority of Polypodium leucotomos formulations (including extracts) related to their quantitative and qualitative polyphenol content and specific photoprotective properties. This article reviews results from a study of six different Polypodium leucotomos extract formulations, comparing their polyphenol and excipient contents and specific photoprotective properties. Consistency was observed primarily with one specific brand of Polypodium leucotomos extract oral capsules, which is also supported by a large body of published evidence.
Keywords: Polypodium leucotomos; antioxidant; photoprotection.