Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory disorder which has been first reported in 2001 by Hamano and colleagues in a patient with autoimmune sclerosing pancreatitis. Almost every organ in the human body can be affected by IgG4-RD from infiltration with IgG4-positive plasma cells. Involvement of lungs with IgG4 is reported previously, but still, there is no clear picture of the pathophysiology behind lung involvement. Here, we are presenting a patient who has IgG4-RD presenting as pseudotumor of the lungs.
Conflict of interest statement
The authors declare that there are no conflicts of interest regarding the publication of this paper.
IgG4-related Disease: With Emphasis on the Biopsy Diagnosis of Autoimmune Pancreatitis and Sclerosing CholangitisS Detlefsen et al. Virchows Arch 472 (4), 545-556. PMID 29196804. - ReviewIn 2011, chronic fibroinflammatory processes occurring simultaneously or metachronously in various organs and associated with elevated IgG4 serum levels and/or tissue inf …
Imaging Features of Immunoglobulin G4-related DiseaseJ Dillon et al. J Med Imaging Radiat Oncol 60 (6), 707-713. PMID 27562417. - ReviewImmunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory condition that was first recognised as a systemic disease in 2003, when patients with autoimmune pancre …
Histopathology of IgG4-Related Autoimmune Hepatitis and IgG4-Related Hepatopathy in IgG4-Related DiseaseY Nakanuma et al. Semin Liver Dis 36 (3), 229-41. PMID 27466793. - Case ReportsImmunoglobulin G4-related disease (IgG4-RD) is a systemic disease involving many organs; it includes IgG4-related sclerosing cholangitis and inflammatory pseudotumor in t …
Reprint Of: Pathologic Manifestations of Immunoglobulin(Ig)G4-related Lung DiseaseES Yi et al. Semin Diagn Pathol 35 (5), 347-351. PMID 30249368.Immunoglobulin(Ig)G4-related disease (IgG4-RD) is a fibroinflammatory condition that can affect virtually any organ and usually presents as tumefactive lesions involving …
A Curious Case of Autoimmune Pancreatitis With IgG4-related Sclerosing CholangitisHH Gonzalez et al. Cureus 11 (2), e4153. PMID 31058036. - Case ReportsImmunoglobulin G4-related sclerosing cholangitis (IgG4-SC) is a novel entity that belongs to the immune-mediated fibroinflammatory class of IgG4-related diseases (IgG4-RD …