Pleomorphic Pulmonary Manifestations of IgG4-Related Disease

Case Rep Rheumatol. 2019 Aug 20;2019:7572869. doi: 10.1155/2019/7572869. eCollection 2019.


Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory disorder which has been first reported in 2001 by Hamano and colleagues in a patient with autoimmune sclerosing pancreatitis. Almost every organ in the human body can be affected by IgG4-RD from infiltration with IgG4-positive plasma cells. Involvement of lungs with IgG4 is reported previously, but still, there is no clear picture of the pathophysiology behind lung involvement. Here, we are presenting a patient who has IgG4-RD presenting as pseudotumor of the lungs.

Publication types

  • Case Reports