Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 12, 2359-2370
eCollection

Assessing the Reporting Quality in Randomized Controlled Trials of Acupuncture for Postherpetic Neuralgia Using the CONSORT Statement and STRICTA Guidelines

Affiliations

Assessing the Reporting Quality in Randomized Controlled Trials of Acupuncture for Postherpetic Neuralgia Using the CONSORT Statement and STRICTA Guidelines

Kun Liu et al. J Pain Res.

Abstract

Background: This study evaluates the reporting quality of randomized controlled trials (RCTs) on acupuncture use for the treatment of postherpetic neuralgia and explores related factors.

Methods: The following six databases PubMed, Embase, Cochrane Library, VIP, CNKI, and SinoMed, were systematically searched from their inception to December 2018. RCTs using acupuncture as an intervention for postherpetic neuralgia were selected and incorporated in this study. The reporting quality was assessed based on the CONSORT statement and the STRICTA guidelines. Regression analyses were also conducted on pre-specified study characteristics searching for factors associated with reporting quality.

Results: A total of 137 RCTs were included in this study. The CONSORT based median OQS was 12 (minimum 3, maximum 29). Of the items comprised in the statement, ten were sufficiently reported (reported in over 70% of trials). The remaining fifty-five items were poorly reported (reported by fewer than 5% of trials). The STRICTA based median OQS was 9 (minimum 2, maximum 15). The results showed that eight of the comprised items were well reported (reported in over 70% of trials), and only three were incompletely reported (reported in fewer than 20% of trials). Based on the CONSORT statement related analysis, a post-2010 publication (β coefficient 2.394, 95% confidence interval [CI] 1.168-3.620) and funding (β coefficient 4.456, 95% CI: 3.009-5.903) represented independent and significant predictors of a high overall reporting quality. However, only a funding source (β coefficient 1.305, 95% CI 0.219-2.391) was associated with an increased OQS based on STRICTA analysis.

Conclusion: The findings indicated that RCTs on acupuncture for PHN generally had a sub-optimal reporting quality, a situation that improved for those published after 2010 or with funding sources. Therefore, rigorous adherence to the CONSORT statement and the STRICTA guidelines should be emphasized in future studies.

Keywords: CONSORT; STRICTA; acupuncture; postherpetic neuralgia; randomized controlled trials.

Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Flow chart of the performed search and selection process.
Figure 2
Figure 2
Distribution of RCT scores with complete reporting of the CONSORT statement items. The blue and red bars represent the before and after 2010 RCT score means according to the CONSORT statement, with 95% CI.
Figure 3
Figure 3
Distribution of RCT scores with complete reporting of the STRICTA checklist items. The blue and red bars represent the before and after 2010 RCT score means with 95% CI according to the STRICTA checklist.

Similar articles

See all similar articles

References

    1. Solomon CG, Johnson RW, Rice AS. Postherpetic neuralgia. N Engl J Med. 2014;371:1526e1533. doi:10.1056/NEJMoa1410490 - DOI - PubMed
    1. Cohen JI. Clinical practice: herpes zoster. N Engl J Med. 2013;369:255e263. doi:10.1056/NEJMcp1302674 - DOI - PMC - PubMed
    1. US Food and Drug Administration (FDA). FDA Approves New Drug Treatment for Long-Term Pain Relief after Shingles Attacks. MD: Silver Spring; 2009.
    1. Yawn BP, Saddier P, Wollan PC, St Sauver JL, Kurland MJ, Sy LS. A population-based study of the incidence and complication rates of herpes zoster before zoster vaccine introduction. Mayo Clin Proc. 2007;82:1341–1349. doi:10.4065/82.11.1341 - DOI - PubMed
    1. Baron R, Wasner G. Prevention and treatment of postherpetic neuralgia. Lancet. 2006;367:186–188. doi:10.1016/S0140-6736(06)68010-0 - DOI - PubMed

LinkOut - more resources

Feedback