A case of severe hypothyroidism due to lenalidomide

Clin Case Rep. 2019 Aug 8;7(9):1747-1749. doi: 10.1002/ccr3.2362. eCollection 2019 Sep.


Lenalidomide, an immunomodulatory drug often used to treat multiple myeloma, can cause hypo- or hyperthyroidism. We present a patient being treated with lenalidomide for 2 years who developed severe hypothyroidism that was complicated by rhabdomyolysis and acute kidney injury. Thyroid function tests should be serially monitored in patients taking lenalidomide.

Keywords: endocrinology; hypothyroidism; lenalidomide; multiple myeloma (Neoplasia‐ myeloma and other plasma cell dyscrasias); rhabdomyolysis.

Publication types

  • Case Reports