Usage of Hydrocolloid-Based Plasters in Patients Who Have Developed Allergic Contact Dermatitis to Isobornyl Acrylate While Using Continuous Glucose Monitoring Systems

J Diabetes Sci Technol. 2020 May;14(3):582-585. doi: 10.1177/1932296819876964. Epub 2019 Sep 20.


Background: Continuous glucose monitoring (CGM) systems replace more and more capillary self-monitoring of blood glucose by patients with diabetes. However, at least a subset of patients experience adverse skin reactions such as severe allergic contact dermatitis (ACD) after prolonged usage of CGM systems. A major allergen isobornyl acrylate (IBOA) has been identified recently.

Objectives: After developing an ACD, patients have difficulties in continuing the usage of their CGM system (and also of, eg, certain patch pumps). Most of such patients look for possibilities to continue the usage of, eg, a CGM system that requires intermittent scanning (iscCGM, Freestyle Libre).

Patients and methods: Eight patients with a known ACD were supplied with different hydrocolloid-based plasters (n = 5 with Hansaplast blister plaster, n = 2 with Cutimed Hydro B from BSN, and n = 1 with Stomahesive baseplate from Convatec). They attached these plasters to their skin underneath their iscCGM system.

Results: All patients were able to continue the usage of this iscCGM system when using such plasters.

Conclusion: Patients with ACD benefit from the usage of such plasters; however, some limitations have to be acknowledged.

Keywords: Freestyle Libre; acrylates; allergic contact dermatitis; hydrocolloid blister plaster; insulin pump; isobornyl acrylate; patch test.

MeSH terms

  • Acrylates / adverse effects*
  • Adult
  • Bandages, Hydrocolloid*
  • Biomarkers / blood
  • Blood Glucose / metabolism*
  • Blood Glucose Self-Monitoring / adverse effects*
  • Blood Glucose Self-Monitoring / instrumentation*
  • Camphanes / adverse effects*
  • Child
  • Dermatitis, Allergic Contact / etiology
  • Dermatitis, Allergic Contact / prevention & control*
  • Diabetes Mellitus, Type 1 / blood
  • Diabetes Mellitus, Type 1 / diagnosis*
  • Equipment Design
  • Female
  • Humans
  • Male
  • Middle Aged
  • Patch Tests
  • Predictive Value of Tests
  • Risk Assessment
  • Risk Factors
  • Treatment Outcome


  • Acrylates
  • Biomarkers
  • Blood Glucose
  • Camphanes
  • isobornyl acrylate