Biosynthesis of fatty acid-derived hydrocarbons: perspectives on enzymology and enzyme engineering

Kun Liu; Shengying Li

doi:10.1016/j.copbio.2019.07.005

Biosynthesis of fatty acid-derived hydrocarbons: perspectives on enzymology and enzyme engineering

Curr Opin Biotechnol. 2020 Apr:62:7-14. doi: 10.1016/j.copbio.2019.07.005. Epub 2019 Sep 17.

Authors

Kun Liu¹, Shengying Li²

Affiliations

¹ State Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong 266237, China.
² State Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong 266237, China; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, Shandong 266237, China. Electronic address: lishengying@sdu.edu.cn.

PMID: 31539870
DOI: 10.1016/j.copbio.2019.07.005

Abstract

Enormous fuel consumption and growing environmental concerns have been spurring development of renewable biofuels. Among various biofuels, fatty acid-derived biohydrocarbons are ideal alternatives to non-renewable fossil fuels due to their closest properties to petroleum-based fuels. In the past decade, novel hydrocarbon-producing enzymes have continuously been discovered and engineered. Here, we review the recent advances in biosynthesis of fatty acid-derived hydrocarbons with emphasis on enzymology and enzyme engineering, based on which some outlooks are provided.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Biofuels
Fatty Acids
Hydrocarbons*
Petroleum*

Substances

Biofuels
Fatty Acids
Hydrocarbons
Petroleum