Cefdinir-induced red stool and purple discoloration of nutritional formula: A case report

Khalid Eljaaly; Samah Alshehri

doi:10.1016/j.jiac.2019.08.014

Cefdinir-induced red stool and purple discoloration of nutritional formula: A case report

J Infect Chemother. 2020 Feb;26(2):286-288. doi: 10.1016/j.jiac.2019.08.014. Epub 2019 Sep 20.

Authors

Khalid Eljaaly¹, Samah Alshehri²

Affiliations

¹ Department of Pharmacy Practice, College of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; Pharmacy Practice and Science Department, College of Pharmacy, University of Arizona, Tucson, AZ, USA. Electronic address: keljaaly@kau.edu.sa.
² Department of Pharmacy Practice, College of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; Pharmacy Practice and Science Department, College of Pharmacy, University of Arizona, Tucson, AZ, USA.

PMID: 31548123
DOI: 10.1016/j.jiac.2019.08.014

Abstract

This case report describes a 4-year-old girl with food aversion who received three separate courses of cefdinir mixed with PediaSure®, an iron-fortified nutritional formula. The patient's stool turned red with variable onset during all three courses of treatment. Moreover, the PediaSure® formula turned purple after mixed with cefdinir, an interaction that has not been previously reported. We recommend that medication counseling for pediatric patients taking cefdinir include a mention of these possible discolorations.

Keywords: Cefdinir; Formula; Purple; Red; Stool; Violet.

Publication types

Case Reports

MeSH terms

Administration, Oral
Anti-Bacterial Agents / administration & dosage
Anti-Bacterial Agents / adverse effects*
Cefdinir / administration & dosage
Cefdinir / adverse effects*
Child, Preschool
Color
Feces / chemistry*
Female
Food, Formulated*
Food-Drug Interactions*
Humans
Iron

Substances

Anti-Bacterial Agents
Cefdinir
Iron