Pseudomonas aeruginosa and cystic fibrosis: unusual bacterial adaptation and pathogenesis

Microbiol Sci. 1986 Oct;3(10):302-8.


Pseudomonas aeruginosa is an adaptable, saprophytic bacterium with the potential to cause a variety of opportunistic infections in compromised hosts. In patients with cystic fibrosis, chronic pulmonary colonization with mucoid alginate-producing mutants of P. aeruginosa is a major cause of morbidity and mortality and is an interesting example of microbial adaptation and host-bacterium interaction.

Publication types

  • Review

MeSH terms

  • Adaptation, Physiological*
  • Bacteriological Techniques
  • Cystic Fibrosis / complications*
  • Cystic Fibrosis / immunology
  • Immune Tolerance
  • Pseudomonas Infections / etiology*
  • Pseudomonas Infections / immunology
  • Pseudomonas aeruginosa / isolation & purification*
  • Pseudomonas aeruginosa / ultrastructure