Mobile phone induced cognitive and neurochemical consequences

J Chem Neuroanat. 2019 Dec;102:101684. doi: 10.1016/j.jchemneu.2019.101684. Epub 2019 Sep 22.


With the rapid advances in technology, extensive use of mobile phones has increased the risk of health problems. This study was performed to find out the effect of mobile phone frequency on male Wistar rats. Animals were divided into two groups (n = 6 in each group). Group one was considered as control and group two (experimental group) was exposed to microwave radiation (2100 MHz) for 4 hours/day (5 days/week) for 3 months. Exposure of microwave radiation frequency showed significant alterations in cholinesterase activity, muscular strength, learning ability and anxiety. MWR exposure was also associated with significant alteration in the oxidative defense system and hippocampus degeneration. Histopathological observations clearly depicted the neural degeneration. Thus, it can be concluded that MWR significantly affects the central nervous system and may lead to many severe illnesses. This study may reveal a platform to understand its toxic effect and can further be used for amendment in current guidelines of mobile radiation.

Keywords: Brain; Cognitive; Hippocampus; Microwave; Oxidative stress.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Behavior, Animal / radiation effects
  • Brain / radiation effects*
  • Cell Phone
  • Cholinesterases / metabolism
  • Hippocampus / radiation effects*
  • Learning / radiation effects*
  • Male
  • Microwaves / adverse effects*
  • Muscle Strength / radiation effects*
  • Oxidative Stress / radiation effects*
  • Rats
  • Rats, Wistar


  • Cholinesterases