Bisphosphonates use in Pachydermoperiostosis

J Assoc Physicians India. 2019 Sep;67(9):87-90.


Pachydermoperiostosis is a rare genetic disorder which commonly presents with clubbing, bone pains and skin changes. The treatment is mostly unsatisfactory. We tried bisphosphonates in our case with encouraging results. We suggest that parenteral bisphosphonates should be tried early in treatment of Pachydermoperiostosis.

Publication types

  • Case Reports

MeSH terms

  • Diphosphonates / therapeutic use*
  • Humans
  • Osteoarthropathy, Primary Hypertrophic / drug therapy*
  • Skin


  • Diphosphonates