Fatigue in Individuals with End Stage Renal Disease

Nephrol Nurs J. Sep-Oct 2019;46(5):497-508.


Fatigue is a subjective overwhelming feeling of tiredness at rest, exhaustion with activity, lack of energy that impedes daily tasks, lack of endurance, or a loss of vigor. Individuals with end stage renal disease (ESRD) experience a high rate and severity of fatigue. Symptom management of fatigue in this population is critical, since fatigue has been linked with lower quality of life and higher mortality rates. In this article, we present a definition and overview of fatigue, a review of factors contributing to fatigue, and ways to manage fatigue in individuals with ESRD.

Keywords: End stage renal disease; fatigue; symptom management.

Publication types

  • Review

MeSH terms

  • Fatigue / etiology*
  • Humans
  • Kidney Failure, Chronic / complications*
  • Kidney Failure, Chronic / nursing
  • Risk Factors