Afatinib Achieved Remarkable Disease Control in a Chinese Patient With Lung Adenocarcinoma Harboring Rare EGFR Exon 18-25 Kinase Domain Duplication

Am J Ther. Sep/Oct 2020;27(5):e535-e537. doi: 10.1097/MJT.0000000000001005.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adenocarcinoma of Lung / diagnosis
  • Adenocarcinoma of Lung / drug therapy*
  • Adenocarcinoma of Lung / genetics
  • Afatinib / pharmacology
  • Afatinib / therapeutic use*
  • Aged
  • Biopsy
  • DNA Mutational Analysis
  • ErbB Receptors / antagonists & inhibitors
  • ErbB Receptors / genetics
  • Exons / genetics
  • Female
  • Humans
  • Lung / diagnostic imaging
  • Lung / pathology
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / genetics
  • Mutation
  • Protein Domains / genetics
  • Response Evaluation Criteria in Solid Tumors
  • Tomography, X-Ray Computed

Substances

  • Afatinib
  • EGFR protein, human
  • ErbB Receptors