Treatment of Catatonia in Frontotemporal Dementia: A Lesson From Zolpidem Test

Clin Neuropharmacol. 2019 Sep/Oct;42(5):186-187. doi: 10.1097/WNF.0000000000000362.

Abstract

Background: During recent years, zolpidem presents a potential but transient treatment option for a large variety of neurologic conditions. Although most cases had disorders of consciousness or movement disorders, there are few reports of beneficial effects of zolpidem on language function.

Case: We present a case of frontotemporal dementia who developed catatonia during her disease course and her refractory speech problem showed dramatic response to zolpidem.

Conclusions: In dementia patients, different catatonic symptoms may show differential responses to the therapeutic agents and, if verbal symptoms are dominant, it is worthy to try zolpidem in the early stage.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Catatonia / drug therapy*
  • Catatonia / etiology
  • Female
  • Frontotemporal Dementia / complications
  • Humans
  • Zolpidem / therapeutic use*

Substances

  • Zolpidem