Effective anti-programmed cell death 1 treatment for chemoresistant gestational trophoblastic neoplasia

Eur J Cancer. 2019 Nov:121:94-97. doi: 10.1016/j.ejca.2019.08.024. Epub 2019 Sep 27.
No abstract available

Keywords: Epithelioid trophoblastic tumour; Gestational trophoblastic neoplasia; MSI; PD-1; Pembrolizumab; Placental site trophoblastic tumour.

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Antibodies, Monoclonal, Humanized / therapeutic use*
  • Drug Resistance, Neoplasm / drug effects*
  • Female
  • Gestational Trophoblastic Disease / drug therapy*
  • Gestational Trophoblastic Disease / pathology
  • Humans
  • Middle Aged
  • Pregnancy
  • Programmed Cell Death 1 Receptor / antagonists & inhibitors
  • Programmed Cell Death 1 Receptor / immunology
  • Remission Induction / methods
  • Treatment Outcome
  • Uterine Neoplasms / drug therapy*
  • Uterine Neoplasms / pathology

Substances

  • Antibodies, Monoclonal, Humanized
  • Programmed Cell Death 1 Receptor
  • pembrolizumab