Randomized controlled trial comparing hydroxychloroquine with pioglitazone as third-line agents in type 2 diabetic patients failing metformin plus a sulfonylurea: A pilot study

J Diabetes. 2020 Jan;12(1):91-94. doi: 10.1111/1753-0407.12989. Epub 2019 Oct 23.
No abstract available

Keywords: anti-inflammation; hydroxychloroquine; insulin sensitivity; pioglitazone.

Publication types

  • Comparative Study
  • Letter
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Antimalarials / therapeutic use
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Drug Therapy, Combination
  • Female
  • Glycated Hemoglobin / analysis
  • Humans
  • Hydroxychloroquine / therapeutic use*
  • Hypoglycemic Agents / therapeutic use
  • Male
  • Metformin / therapeutic use*
  • Middle Aged
  • Outcome Assessment, Health Care / methods
  • Outcome Assessment, Health Care / statistics & numerical data
  • Pilot Projects
  • Pioglitazone / therapeutic use*
  • Prospective Studies
  • Sulfonylurea Compounds / therapeutic use*
  • Treatment Failure

Substances

  • Antimalarials
  • Glycated Hemoglobin A
  • Hypoglycemic Agents
  • Sulfonylurea Compounds
  • Hydroxychloroquine
  • Metformin
  • Pioglitazone