Objectives: Some early studies indicated lower survival with longer time from diagnosis to cancer treatment, but others showed the reverse. We investigated time to treatment of colorectal cancer and associations with survival.
Setting and participants: Clinical registry data for colorectal cancer cases diagnosed in 2000-2010 at four major public hospitals in South Australia and treated by surgery (n=1675), radiotherapy (n=616) and/or systemic therapy (n=1556).
Design: A historic cohort design, with rank-order tests for ordinal clinical and sociodemographic predictors and multiple logistic regression for comparing time from diagnosis to treatment. Unadjusted Kaplan-Meier estimates and adjusted Cox proportional hazards regression were used to investigate disease-specific survival by time to treatment.
Outcome measures: Time to treatment and survival from diagnosis to death from colorectal cancer.
Treatment (any type) commenced for 87% of surgical cases
The lower survival
Keywords: Oncology epidemiology; colorectal surgery; protocols & guidelines; public health; quality in healthcare.
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