A rare cause of bleeding in two Indian families with congenital alpha-2-antiplasmin deficiency

Haemophilia. 2019 Nov;25(6):e370-e372. doi: 10.1111/hae.13851. Epub 2019 Oct 2.

Authors

Aniket Prabhudesai¹, Shrimati Shetty¹, Chandrakala Shanmukhaiah², Siddhesh Kalantri³, Maitreyee Bhattacharyya³, Bipin Kulkarni¹

Affiliations

¹ Department of Thrombosis and Haemostasis, National Institute of Immunohaematology (ICMR), KEM Hospital Campus, Mumbai, India.
² Department of Haematology, Seth GS Medical College and KEM Hospital, Mumbai, India.
³ Institute of Hematology and Transfusion Medicine, Medical College and Hospital Kolkata, Kolkata, India.

PMID: 31577375
DOI: 10.1111/hae.13851

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adult
Codon, Nonsense
Female
Hemorrhage / blood
Hemorrhage / epidemiology
Hemorrhage / etiology*
Hemorrhage / genetics
Hemorrhagic Disorders / blood
Hemorrhagic Disorders / complications*
Hemorrhagic Disorders / epidemiology
Hemorrhagic Disorders / genetics
Humans
India / epidemiology
Male
Middle Aged
Pedigree
alpha-2-Antiplasmin / analysis
alpha-2-Antiplasmin / deficiency*
alpha-2-Antiplasmin / genetics

Substances

Codon, Nonsense
SERPINF2 protein, human
alpha-2-Antiplasmin

Supplementary concepts

Anti-plasmin deficiency, congenital

Associated data

GENBANK/KY972265
GENBANK/MG878957