Adequate reconstruction of sternal defects is critical for function and quality of life. Reconstructive techniques have historically included a rigid component, most often a synthetic prosthesis, but these are associated with complications related to presence of a foreign body and the loss of native bone's flexibility and growth capability. Recently, biologic mesh has been used as an alternative for reconstructions of the chest wall, but not the sternum. We present the case of a large sternal defect after chondrosarcoma resection reconstructed with porcine acellular dermal matrix and soft tissue flaps, without rigid component, and with excellent patient outcome through 2 years of follow-up.
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