Adult Primary Brain Neoplasm, Including 2016 World Health Organization Classification

Kevin Yuqi Wang; Melissa M Chen; Christie M Malayil Lincoln

doi:10.1016/j.rcl.2019.07.004

Adult Primary Brain Neoplasm, Including 2016 World Health Organization Classification

Radiol Clin North Am. 2019 Nov;57(6):1147-1162. doi: 10.1016/j.rcl.2019.07.004. Epub 2019 Aug 16.

Authors

Kevin Yuqi Wang¹, Melissa M Chen², Christie M Malayil Lincoln³

Affiliations

¹ Department of Radiology, Baylor College of Medicine, One Baylor Plaza, MS360, Houston, TX 77030, USA.
² Department of Diagnostic Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1482, Houston, TX 77030, USA.
³ Department of Radiology, Baylor College of Medicine, One Baylor Plaza, MS360, Houston, TX 77030, USA. Electronic address: Christie.Lincoln@bcm.edu.

PMID: 31582041
DOI: 10.1016/j.rcl.2019.07.004

Abstract

In 2016, the World Health Organization (WHO) central nervous system (CNS) classification scheme incorporated molecular parameters in addition to traditional microscopic features for the first time. Molecular markers add a level of objectivity that was previously missing for tumor categories heavily dependent on microscopic observation for pathologic diagnosis. This article provides a brief discussion of the major 2016 updates to the WHO CNS classification scheme and reviews typical MR imaging findings of adult primary CNS neoplasms, including diffuse infiltrating gliomas, ependymal tumors, neuronal/glioneuronal tumors, pineal gland tumors, meningiomas, nerve sheath tumors, solitary fibrous tumors, and lymphoma.

Keywords: Adult primary neoplasm; Central nervous system; MR imaging; WHO.

Publication types

Review

MeSH terms

Adult
Brain / diagnostic imaging
Brain Neoplasms / classification*
Brain Neoplasms / diagnostic imaging*
Humans
Magnetic Resonance Imaging / methods*
Tomography, X-Ray Computed / methods*
World Health Organization*