Recent advances in the epidemiology, diagnosis, and management of Trichomonas vaginalis infection

F1000Res. 2019 Sep 20:8:F1000 Faculty Rev-1666. doi: 10.12688/f1000research.19972.1. eCollection 2019.


Trichomonas vaginalis is the most common, curable non-viral sexually transmitted infection (STI) worldwide. Despite this burden of disease, it is not currently a reportable disease in the United States. Recent advances in the epidemiology, diagnosis, and management of T. vaginalis infection are described in this article. This includes updated global and U.S. prevalence data in women and men as well as recent epidemiological data in HIV-infected individuals and pregnant women. Advances in molecular diagnostics are also reviewed, as are data from recent clinical trials regarding the treatment of trichomonas in women.

Keywords: STI; Trichomonas vaginalis; vaginal infections.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Coinfection
  • Female
  • HIV Infections / complications
  • Humans
  • Male
  • Pregnancy
  • Sexually Transmitted Diseases / diagnosis
  • Sexually Transmitted Diseases / epidemiology
  • Sexually Transmitted Diseases / therapy
  • Trichomonas Infections / diagnosis*
  • Trichomonas Infections / epidemiology*
  • Trichomonas Infections / therapy*
  • Trichomonas vaginalis
  • United States