"Plis de passage" Deserve a Role in Models of the Cortical Folding Process

Brain Topogr. 2019 Nov;32(6):1035-1048. doi: 10.1007/s10548-019-00734-8. Epub 2019 Oct 3.

Abstract

Cortical folding is a hallmark of brain topography whose variability across individuals remains a puzzle. In this paper, we call for an effort to improve our understanding of the pli de passage phenomenon, namely annectant gyri buried in the depth of the main sulci. We suggest that plis de passage could become an interesting benchmark for models of the cortical folding process. As an illustration, we speculate on the link between modern biological models of cortical folding and the development of the Pli de Passage Frontal Moyen (PPFM) in the middle of the central sulcus. For this purpose, we have detected nine interrupted central sulci in the Human Connectome Project dataset, which are used to explore the organization of the hand sensorimotor areas in this rare configuration of the PPFM.

Keywords: Central sulcus; Cortical folding; Pli de passage; Sulcal pits; Sulcal roots.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cerebral Cortex / anatomy & histology*
  • Cerebral Cortex / physiology
  • Connectome
  • Hand
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Models, Biological
  • Occipital Lobe / anatomy & histology*
  • Occipital Lobe / physiology
  • Sensorimotor Cortex / anatomy & histology
  • Sensorimotor Cortex / physiology