Respiratory complications after adenotonsillectomy in high-risk children with obstructive sleep apnea: A retrospective cohort study

Acta Anaesthesiol Scand. 2020 Mar;64(3):292-300. doi: 10.1111/aas.13488. Epub 2019 Oct 23.

Abstract

Background: Obstructive sleep apnea (OSA) occurs in 1%-4% of children; adenotonsillectomy is an effective treatment. Mortality/severe brain injury occurs among 0.6/10 000 adenotonsillectomies; in children, 60% are secondary to airway/respiratory events. Earlier studies identified that children aged <2 years, extremes of weight, with co-morbidities of craniofacial, neuromuscular, cardiac/respiratory disease, or severe OSA are at high risk for adverse post-operative respiratory events (AE). We aimed to: Firstly, investigate which risk factors were associated with AEs either in the post-anesthesia care unit (PACU), pediatric intensive care unit (PICU), or both in this population. Secondly, we investigated factors associated with post-operative PICU AE despite no event in the PACU in order to predict need of post-operative PICU after their PACU stay.

Methods: Retrospective study of children admitted to the PICU after adenotonsillectomy between 08/2006-09/2015. Demographics, risk factors, and occurrence of AE (oxygen saturation <92, stridor, bronchospasm, pneumonia, pulmonary edema, re-intubation) were recorded.

Results: During the studied time period 4029 tonsil/adenoid procedures were performed in 3997 children. 179, admitted to the PICU post-operatively, met criteria for analysis. PICU AEs occurred in 59%: 44%-83% in any particular risk category. PACU AEs occurred in 42%. Of those with PACU events: 92% suffered AEs in the PICU; however, 35% of those without a PACU AE still suffered a PICU AE.

Conclusions: Among high-risk children undergoing TA, absence of adverse events in PACU during a 2-hour observation period does not predict absence of subsequent AEs in the PICU.

Keywords: intensive care; obstructive sleep apnea; pediatric tonsillectomy and adenoidectomy.

MeSH terms

  • Adenoidectomy / adverse effects*
  • Causality
  • Child, Preschool
  • Cohort Studies
  • Comorbidity
  • Female
  • Humans
  • Israel / epidemiology
  • Male
  • Postoperative Complications / epidemiology*
  • Respiration Disorders / epidemiology*
  • Retrospective Studies
  • Risk
  • Severity of Illness Index
  • Sleep Apnea, Obstructive / epidemiology*
  • Tonsillectomy / adverse effects*
  • Treatment Outcome