Declining incidence of dementia: A national registry-based study over 20 years

Alzheimers Dement. 2019 Nov;15(11):1383-1391. doi: 10.1016/j.jalz.2019.07.006. Epub 2019 Oct 3.

Abstract

Introduction: The aim of this study was to investigate the registry-based national time trends in incidence and prevalence rates of dementia from 1996 to 2015.

Methods: We assessed annual incidence and prevalence using longitudinal data from nationwide registries on dementia status and demographics on all residents ≥ 65 years old in Denmark.

Results: Our population comprised 2 million people, of whom 152,761 were diagnosed with dementia. The age- and sex-adjusted incidence rate increased, on average, by 9% annually from 1996 to 2003, followed by a 2% annual decline, while total prevalence increased during the whole period.

Discussion: This is the first study to report continuous time trends of incidence and prevalence in an entire national population. The incidence rate has declined steadily since 2003, while the total prevalence is still increasing. Future health care planning on prevention and treatment of dementia should take these findings into account.

Keywords: Dementia; Epidemiology; Incidence; Nationwide study; Prevalence; Registry study; Time trend.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Dementia / epidemiology*
  • Denmark / epidemiology
  • Female
  • Forecasting
  • Humans
  • Incidence
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Prevalence
  • Registries / statistics & numerical data*
  • Risk Factors
  • Time Factors