Vaccinating Calves in the Face of Maternal Antibodies: Challenges and Opportunities

M Claire Windeyer; Lisa Gamsjäger

doi:10.1016/j.cvfa.2019.07.004

Vaccinating Calves in the Face of Maternal Antibodies: Challenges and Opportunities

Vet Clin North Am Food Anim Pract. 2019 Nov;35(3):557-573. doi: 10.1016/j.cvfa.2019.07.004.

Authors

M Claire Windeyer¹, Lisa Gamsjäger²

Affiliations

¹ Department of Production Animal Health, University of Calgary Faculty of Veterinary Medicine, 11877 85th Street NW, Calgary, Alberta T3R 1J3, Canada. Electronic address: c.windeyer@ucalgary.ca.
² Department of Production Animal Health, University of Calgary Faculty of Veterinary Medicine, 11877 85th Street NW, Calgary, Alberta T3R 1J3, Canada.

PMID: 31590902
DOI: 10.1016/j.cvfa.2019.07.004

Abstract

A growing body of evidence has shown that calves can mount an immune response when vaccinated in the face of maternal antibodies (IFOMA), albeit inconsistently and often in ways that differ from seronegative calves or older cattle. Several previous reviews have endeavored to explain bovine neonatal immunology and have documented the issue of vaccinating young calves. However, as preweaning vaccination becomes more common in both beef and dairy production systems, so too has research on the impacts of such vaccination programs. This article aims to briefly review the challenges and opportunities for vaccinating calves IFOMA.

Keywords: Disease prevention; Maternal antibodies; Neonatal calf; Passive immunity; Vaccination.

Publication types

Review

MeSH terms

Animals
Cattle
Cattle Diseases / prevention & control
Female
Immunity, Maternally-Acquired / immunology*
Maternal-Fetal Exchange / immunology
Pregnancy
Vaccination / methods
Vaccination / veterinary*