Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure

Analyst. 2019 Nov 18;144(23):6850-6857. doi: 10.1039/c9an01312a.


Despite its crucial role, the placenta is the least understood human organ. Recent clinical studies indicate a direct association between placental calcification and maternal and offspring health. This study reveals distinct characteristics of minerals formed during gestational ageing using cutting-edge nano-analytical characterization and paves the way for investigations focused on the identification of potential markers for disease risks in a clinical setting based on atypical placental mineral fingerprints.

MeSH terms

  • Animals
  • Calcification, Physiologic / physiology*
  • Cats
  • Dogs
  • Female
  • Horses
  • Humans
  • Microscopy, Electron, Scanning
  • Minerals / analysis*
  • Minerals / chemistry
  • Minerals / metabolism
  • Placenta / metabolism*
  • Placenta / ultrastructure
  • Pregnancy
  • Rabbits
  • Spectrum Analysis
  • Tomography, X-Ray Computed


  • Minerals