Papillary Hemangioma: An Under-Recognized Entity Not to Be Confused With Glomeruloid Hemangioma

Am J Dermatopathol. 2020 Mar;42(3):211-214. doi: 10.1097/DAD.0000000000001546.


Papillary hemangioma is a recently described benign hemangioma that typically presents on the head and neck of otherwise healthy individuals. It comprises branching papillary structures that protrude into the lumen of ectatic thin-walled vessels. Glomeruloid hemangioma (GH) is a similar, but unique, entity that occurs in patients with POEMS syndrome. The additional clinical implications of GH make distinction from papillary hemangioma critical. An additional case is herein presented and the literature on the subject reviewed. Potential differential diagnoses are discussed, with particular emphasis on the distinction from GH.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Diagnosis, Differential
  • Head and Neck Neoplasms / diagnosis*
  • Head and Neck Neoplasms / pathology*
  • Hemangioma / diagnosis*
  • Hemangioma / pathology*
  • Humans
  • Male