We examine the influence of superconductivity on the magneto-transport properties of a ferromagnetic Ni nanowire connected to Nb electrodes. We show experimentally and confirm theoretically that the Nb/Ni interface plays an essential role in the electron transport through the device. Just below the superconducting transition, a strong inverse proximity effect from the nanowire suppresses superconducting correlations at Nb/Ni interfaces, resulting in a conventional anisotropic magneto-resistive response. At lower temperatures however, the Nb electrodes operate as superconducting shunts. As the result, the magneto-resistance exhibits a strongly growing hysteretic behavior accompanied by a series of saw-like jumps. The latter are associated with the penetration/escape of individual Abrikosov vortices that influence non-equilibrium processes at the Nb/Ni interface. These effects should be taken into account when designing superconducting quantum nano-hybrids involving ferromagnetic nanowires.