Recent advances in nontuberculous mycobacterial lung infections

David Horne; Shawn Skerrett

doi:10.12688/f1000research.20096.1

Recent advances in nontuberculous mycobacterial lung infections

F1000Res. 2019 Oct 1:8:F1000 Faculty Rev-1710. doi: 10.12688/f1000research.20096.1. eCollection 2019.

Authors

David Horne¹, Shawn Skerrett¹

Affiliation

¹ Division of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Harborview Medical Center, Seattle, USA.

Abstract

Nontuberculous mycobacteria (NTM) are members of the Mycobacterium genus other than Mycobacterium tuberculosis complex and Mycobacterium leprae. NTM are widely distributed in the environment and are increasingly recognized as causes of chronic lung disease that can be challenging to treat. In this brief review, we consider recent developments in the ecology, epidemiology, natural history, and treatment of NTM lung disease with a focus on Mycobacterium avium complex (MAC) and Mycobacterium abscessus complex .

Keywords: Non-tuberculous mycobacteria.

Publication types

Review

MeSH terms

Humans
Lung Diseases / diagnosis*
Lung Diseases / microbiology
Lung Diseases / therapy*
Mycobacterium Infections, Nontuberculous / diagnosis*
Mycobacterium Infections, Nontuberculous / therapy*
Mycobacterium abscessus
Mycobacterium avium Complex

Grants and funding

The author(s) declared that no grants were involved in supporting this work.