Photo-responsive materials with strong cell trapping ability for light-guided manipulation of nonadherent cells

Biomater Sci. 2019 Nov 1;7(11):4514-4518. doi: 10.1039/c9bm01200a. Epub 2019 Oct 11.


We report a photo-cleavable material for tight trapping of nonadherent cells to substrate surfaces. Model immunocytes were selectively trapped in a non-irradiated area as single cells after the projection of a light pattern and withstood high-speed laminar flow, achieving light-guided cell release from the substrates.

MeSH terms

  • Animals
  • Cell Line
  • Cell Separation*
  • Light*
  • Lipids / chemistry*
  • Mice
  • Microfluidic Analytical Techniques
  • Molecular Structure
  • Particle Size
  • Photochemical Processes
  • Polyethylene Glycols / chemistry*
  • Surface Properties


  • Lipids
  • Polyethylene Glycols