Centralization tendencies of retroperitoneal lymph node dissection for testicular cancer in Germany? A total population-based analysis from 2006 to 2015

World J Urol. 2020 Jul;38(7):1765-1772. doi: 10.1007/s00345-019-02972-8. Epub 2019 Oct 11.

Abstract

Introduction: Retroperitoneal lymph node dissection (RPLND) is a standard treatment in the management of metastatic testicular cancer. Due to modified treatment algorithms, it is becoming less frequent.

Materials and methods: We analyzed data from the nationwide German hospital billing database covering 2006-2015. Cases with a testicular cancer diagnosis combined with RPLND were included. We assessed the length of hospital stay (LOS), blood transfusion, and in-hospital mortality stratified for surgical approach, hospital characteristics, and annual caseload. Annual hospital caseload categories were defined as low (< 4), medium (4-10), and high (> 10). We supplemented tumor incidence and staging data from the German cancer registry (60% of population).

Results: 4926 cases were included with decreasing annual caseload numbers from 623 in 2006 to 382 in 2015. The incidence of testicular cancer and higher tumor stages remained stable. High-volume hospitals performed 19.4%, medium-volume hospitals 43.7%, and low-volume hospitals 36.8% RPLNDs. Low- abd medium-volume hospitals declined, while high-volume hospitals (n = 5) maintained their annual caseload. Overall in-hospital mortality was 0.47%. Blood transfusion rates were higher in high-volume centers assumedly due to selection of more complex cases. However, high-volume hospitals showed a shorter LOS with 10.5 vs. 11.2 (medium volume), and 12.7 days (low volume).

Conclusion: Total numbers of RPLND have declined from 2006 to 2015, while tumor incidences and stages remained fairly stable. Constant reduction of indication in guidelines contributes to this finding. High-volume hospitals achieve shorter hospital stays in spite of assumedly more complex and extensive cases. There is a modest trend towards unregulated centralization.

Keywords: Centralization; Health services research; Population-based analysis; Retroperitoneal lymph node dissection; Testicular cancer.

MeSH terms

  • Adult
  • Germany
  • Hospitals, High-Volume / statistics & numerical data
  • Hospitals, Low-Volume / statistics & numerical data
  • Humans
  • Lymph Node Excision / methods
  • Lymph Node Excision / statistics & numerical data*
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Retroperitoneal Space
  • Testicular Neoplasms / pathology
  • Testicular Neoplasms / surgery*
  • Time Factors
  • Young Adult