National Trends in Incidence of Purulent Skin and Soft Tissue Infections in Patients Presenting to Ambulatory and Emergency Department Settings, 2000-2015

Clin Infect Dis. 2020 Jun 10;70(12):2715-2718. doi: 10.1093/cid/ciz977.


Nationally representative data from 2000-2015 demonstrated a rise in the incidence of outpatient visits for skin infections, peaking in 2010-2013, followed by a plateau. While cephalexin was the most frequently prescribed antibiotic at the beginning, trimethoprim-sulfamethoxazole was most frequently prescribed by the end of the study period.

Keywords: ambulatory; antibiotic prescriptions; incidence; skin and soft tissue infection.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Cephalexin
  • Emergency Service, Hospital
  • Humans
  • Incidence
  • Skin Diseases, Infectious* / drug therapy
  • Skin Diseases, Infectious* / epidemiology
  • Soft Tissue Infections* / drug therapy
  • Soft Tissue Infections* / epidemiology


  • Anti-Bacterial Agents
  • Cephalexin