A multicenter study of oral sarcomas in Brazil

Oral Dis. 2020 Jan;26(1):43-52. doi: 10.1111/odi.13211. Epub 2019 Nov 6.


Objectives: The aim of this study was to investigate the prevalence of oral sarcomas from geographic regions of Brazil.

Materials and methods: A cross-sectional study was conducted on biopsies obtained from January 2007 to December 2016 at twelve Brazilian oral and maxillofacial pathology centres. Gender, age, evolution time, clinical aspects, tumour location, tumour size at diagnosis, radiographic aspects and histopathological diagnosis were evaluated. Data were analysed using descriptive statistical methods.

Results: From 176,537, a total of 200 (0.11%) oral sarcomas were reported, and the most prevalent were osteosarcomas (74 cases; 37%) and Kaposi's sarcomas (52 cases; 26%). Males were more affected than females at a mean age of 32.2 years old (range of 3-87 years). The most common symptoms were swelling¸ localised pain and bleeding at a mean evolution time of 5.14 months (range <1-156 months). The lesions were mostly observed in the mandible (90 cases; 45%), with a mean tumour size of 3.4 cm (range of 0.3-15 cm). Radiographically, the lesions presented a radiolucent aspect showing cortical bone destruction and ill-defined limits.

Conclusions: Oral sarcomas are rare lesions with more than 50 described subtypes. Osteosarcomas and Kaposi's sarcomas were the main sarcomas of the oral cavity in Brazil.

Keywords: epidemiology; maxillofacial regions; mesenchymal tumours; mouth; sarcomas.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy
  • Brazil / epidemiology
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mouth Neoplasms / epidemiology*
  • Osteosarcoma / epidemiology
  • Retrospective Studies
  • Sarcoma / epidemiology*
  • Sarcoma, Kaposi / epidemiology
  • Young Adult