The risks of smoking during pregnancy are serious and well-documented. It is assumed that we do not identify all pregnant women with tobacco and nicotine consumption. Therefore, a new national Danish guideline presents a new screening and referral model for use from early pregnancy. All tobacco and nicotine consumption must be covered, including previous smoking and exposure to tobacco smoke. All pregnant women should be offered help to stop smoking or use of smokeless tobacco and help to avoid any exposure to tobacco smoke. Reference can be made to the municipality, Stoplinien and/or the hospital.