Prevalence of sickle cell disease and sickle cell trait among children admitted to Al Fashir Teaching Hospital North Darfur State, Sudan

Mudathir A Adam; Nassreldeen K Adam; Babiker A Mohamed

doi:10.1186/s13104-019-4682-5

Prevalence of sickle cell disease and sickle cell trait among children admitted to Al Fashir Teaching Hospital North Darfur State, Sudan

BMC Res Notes. 2019 Oct 16;12(1):659. doi: 10.1186/s13104-019-4682-5.

Authors

Mudathir A Adam¹, Nassreldeen K Adam², Babiker A Mohamed³

Affiliations

¹ Faculty of Medical Laboratory Science, Al Fashir University, Al Fashir, Sudan. mudathirdodo@gmail.com.
² Faculty of Medical Laboratory Science, Al Fashir University, Al Fashir, Sudan.
³ Pathology Department, Faculty of Medicine, Karari University, Khartoum, Sudan.

Abstract

Objective: It is estimated that 50% to 90% of infants born with (SCA) in sub-Saharan Africa die before 5 years old. Northern Darfur State at western Sudan region has a multiethnic population with a high frequency of sickle cell anaemia, but little about it is published. This study aimed to determine the prevalence of sickle cell anaemia among children admitted to Al Fashir Teaching Hospital in Al Fashir, Northern Darfur State, Sudan.

Results: The prevalence of sickle cell disease by haemoglobin electrophoresis among these 400 children patients was 59 (14.8%). Sickle cell trait patients were 11.3% and Sickle cell disease positive patients were 3.5%. Individuals with SCA have consistently low blood Hb concentration, normal MCV and high mean WBC's. Individuals with sickle cell trait had haematological parameters near to those of normal individuals.

Keywords: Al Fashir; Children; Hb AS; Hb SS; Hb electrophoresis; Sickle cell disease.

MeSH terms

Anemia, Sickle Cell / epidemiology*
Child
Child, Preschool
Female
Hospitals, Teaching*
Humans
Infant
Male
Patient Admission / statistics & numerical data*
Prevalence
Sickle Cell Trait / epidemiology*
Sudan / epidemiology