Structural gene encoding human factor XII is located at 5q33-qter

Somat Cell Mol Genet. 1988 Mar;14(2):217-21. doi: 10.1007/BF01534407.

Abstract

The gene encoding human factor XII (F12) or Hageman factor has been mapped to 5q33-qter. This has been achieved by analyzing the results obtained from hybridizing a cloned fragment from the factor XII gene to a panel of human-hamster somatic cell hybrid DNAs and also by in situ hybridization to normal human metaphase cells. The previously reported results localizing F12 to 6p23 are discussed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromosome Banding
  • Chromosome Mapping*
  • Chromosomes, Human, Pair 5*
  • Cricetinae
  • Factor XII / genetics*
  • Genes*
  • Humans
  • Hybrid Cells
  • Karyotyping
  • Sequence Homology, Nucleic Acid

Substances

  • Factor XII