PIEZO1 gain-of-function mutations delay reticulocyte maturation in hereditary xerocytosis

Affiliations

• ¹ School of Biochemistry, University of Bristol, Bristol, UK.
• ² NIHR Blood and Transplant Research Unit in Red Cell Products, University of Bristol, Bristol, UK.
• ³ School of Physiology, Pharmacology and Neuroscience, University of Bristol,Britsol, UK.
• ⁴ Amsterdam UMC, University of Amsterdam, Department of Biomedical Engineering and Physics, Amsterdam, the Netherlands.
• ⁵ Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
• ⁶ Van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
• ⁷ UOC Ematologia, UOS Fisiopatologia delle Anemie, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.
• ⁸ School of Biochemistry, University of Bristol, Bristol, UK ash.m.toye@bristol.ac.uk.
• ⁹ Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant (NHSBT), Bristol, UK.
• ¹⁰ School of Biochemistry, University of Bristol, Bristol, UK t.satchwell@bristol.ac.uk.