Presumed antiphospholipid syndrome and thrombotic thrombocytopenic purpura: An infrequent association

Clin Case Rep. 2019 Sep 9;7(10):1984-1988. doi: 10.1002/ccr3.2416. eCollection 2019 Oct.


Antiphospholipid syndrome (APS) is an autoimmune disease that demonstrates antiphospholipid antibodies that cause hypercoagulability and leads to venous and arterial thrombosis. Autoantibodies to a disintegrin-like and metalloprotease with thrombospondin type I motif, member 13 (ADAMTS 13) play a role in the microthrombosis of thrombotic thrombocytopenic purpura in APS patients.

Keywords: ADAMTS13; antiphospholipid syndrome; disintegrin‐like and metalloprotease; thrombotic thrombocytopenic purpura.

Publication types

  • Case Reports