SnapShot: S-Phase Entry and Exit

Cell. 2019 Oct 17;179(3):802-802.e1. doi: 10.1016/j.cell.2019.09.031.


S-phase entry and exit are regulated by hundreds of protein complexes that assemble "just in time," orchestrated by a multitude of distinct events. To help understand their interplay, we have created a tailored visualization based on the Minardo layout, highlighting over 80 essential events. This complements our earlier visualization of M-phase, and both can be displayed together, giving a comprehensive overview of the events regulating the cell division cycle. To view this SnapShot, open or download the PDF.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Cycle / genetics*
  • Cell Division / genetics
  • Cyclin B / genetics
  • Cyclin D / genetics
  • Cyclin-Dependent Kinases / genetics
  • G2 Phase / genetics
  • Humans
  • Mitosis / genetics*
  • Multiprotein Complexes / genetics*
  • Phosphorylation / genetics
  • Proteasome Endopeptidase Complex / genetics
  • S Phase / genetics*


  • Cyclin B
  • Cyclin D
  • Multiprotein Complexes
  • Cyclin-Dependent Kinases
  • Proteasome Endopeptidase Complex