Self-renewal and differentiation in squamous cell carcinomas

Aging (Albany NY). 2019 Oct 18;11(20):8736-8738. doi: 10.18632/aging.102381. Epub 2019 Oct 18.

Authors

Ana Sastre-Perona¹, Steven Hoang-Phou¹, Markus Schober^{1

2

3}

Affiliations

¹ The Ronald O. Perelman Department of Dermatology, NYU School of Medicine, New York, NY 10016, USA.
² Department of Cell Biology, NYU School of Medicine, New York, NY 10016, USA.
³ Perlmutter Cancer Center, NYU School of Medicine, New York, NY 10016, USA.

No abstract available

Keywords: KLF4; PITX1; SOX2; cancer stem cells; self-renewal; squamous cell carcinoma; transcriptional networks.

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Carcinoma, Squamous Cell / metabolism*
Cell Differentiation
Cell Self Renewal*
Gene Expression Regulation, Neoplastic
Humans
Kruppel-Like Factor 4
Mice
Neoplastic Stem Cells / physiology*
Paired Box Transcription Factors / genetics
Paired Box Transcription Factors / metabolism
SOXB1 Transcription Factors / genetics
SOXB1 Transcription Factors / metabolism

Substances

KLF4 protein, human
Klf4 protein, mouse
Kruppel-Like Factor 4
Paired Box Transcription Factors
SOX2 protein, human
SOXB1 Transcription Factors
Sox2 protein, mouse
homeobox protein PITX1