Many Ways to Build a Polyp

Detlev Arendt

doi:10.1016/j.tig.2019.09.003

Many Ways to Build a Polyp

Trends Genet. 2019 Dec;35(12):885-887. doi: 10.1016/j.tig.2019.09.003. Epub 2019 Oct 16.

Author

Detlev Arendt¹

Affiliation

¹ Developmental Biology Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69012 Heidelberg, Germany; Centre for Organismal Studies, University of Heidelberg, Im Neuenheimer Feld 230, 69120 Heidelberg, Germany. Electronic address: arendt@embl.de.

PMID: 31629552
DOI: 10.1016/j.tig.2019.09.003

Abstract

The freshwater cnidarian Hydra has been studied for centuries for its unique regenerative capacities. Whole-body single-cell transcriptomics now reveal cellular lineages and gene regulatory networks that build the Hydra polyp. For the first time, transcription factor signatures allow direct comparison of the polyp body plan between Hydra and sea anemone.

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MeSH terms

Animals
Cell Differentiation
Hydra*