Methylphenidate does not affect convergent and divergent creative processes in healthy adults

Neuroimage. 2020 Jan 15:205:116279. doi: 10.1016/j.neuroimage.2019.116279. Epub 2019 Oct 17.

Abstract

An increasing number of healthy people use methylphenidate, a psychostimulant that increases dopamine and noradrenaline transmission in the brain, to help them focus over extended periods of time. While methylphenidate has been shown to facilitate some cognitive functions, like focus and distractor-resistance, the same drug might also contribute to cognitive impairment, for example, in creativity. In this study, we investigated whether acute administration of a low oral dose (20 mg) of methylphenidate affected convergent and divergent creative processes in a sample of young healthy participants. Also, we explored whether such effects depended on individual differences in ADHD symptoms and working memory capacity. Contrary to our expectations, methylphenidate did not affect participants' creative performance on any of the tasks. Also, methylphenidate effects did not depend on individual differences in trait hyperactivity-impulsivity or baseline working memory capacity. Thus, although the effects of methylphenidate on creativity might be underestimated in our study due to several methodological factors, our findings do not suggest that methylphenidate impairs people's ability to be creative.

Keywords: ADHD; Creativity; Dopamine; Flexibility; Methylphenidate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Attention Deficit Disorder with Hyperactivity / physiopathology
  • Central Nervous System Stimulants / administration & dosage
  • Central Nervous System Stimulants / adverse effects
  • Central Nervous System Stimulants / pharmacology*
  • Creativity*
  • Female
  • Humans
  • Impulsive Behavior / physiology
  • Male
  • Memory, Short-Term / physiology
  • Methylphenidate / administration & dosage
  • Methylphenidate / adverse effects
  • Methylphenidate / pharmacology*
  • Personality / physiology
  • Thinking / drug effects*
  • Young Adult

Substances

  • Central Nervous System Stimulants
  • Methylphenidate