Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease. Various classification systems and phenotypes have been proposed. This review highlights the current classifications of COPD, describes the major phenotypes and provides a blue print for risk assessment of COPD. It is likely that more phenotypes and endotypes of COPD will be described paving the way to personalized medicine for patients with COPD.
Keywords: COPD classification; COPD phenotype.
2019 Journal of Thoracic Disease. All rights reserved.
Conflict of interest statement
Conflicts of Interest: The author has no conflicts of interest to declare.
Personalized medicine and chronic obstructive pulmonary disease.Curr Opin Pulm Med. 2017 May;23(3):241-246. doi: 10.1097/MCP.0000000000000377. Curr Opin Pulm Med. 2017. PMID: 28257315 Review.
What does endotyping mean for treatment in chronic obstructive pulmonary disease?Lancet. 2017 Sep 2;390(10098):980-987. doi: 10.1016/S0140-6736(17)32136-0. Lancet. 2017. PMID: 28872030 Review.
[PERSONALIZED MEDICINE: CHRONIC OBSTRUCTIVE PULMONARY DISEASE TREATMENT].Rev Med Liege. 2015 May-Jun;70(5-6):310-5. Rev Med Liege. 2015. PMID: 26285458 Review. French.
[Clinical phenotypes in chronic obstructive pulmonary disease].Rev Med Chil. 2012 Jul;140(7):926-33. doi: 10.4067/S0034-98872012000700016. Rev Med Chil. 2012. PMID: 23282708 Review. Spanish.
Current concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised management.Lancet. 2015 May 2;385(9979):1789-1798. doi: 10.1016/S0140-6736(15)60693-6. Lancet. 2015. PMID: 25943943 Free PMC article. Review.