Seroprevalence of Toxoplasma gondii in horses: A global systematic review and meta-analysis

Acta Trop. 2020 Jan;201:105222. doi: 10.1016/j.actatropica.2019.105222. Epub 2019 Oct 19.

Abstract

Toxoplasmosis, one of the most common zoonoses worldwide, is caused by Toxoplasma gondii. T. gondii can infect almost all warm-blooded animals, including humans. Horses are an intermediate host of T. gondii, representing a potential risk for humans. To determine the T. gondii seroprevalence in horses worldwide, a global meta-analysis was conducted. A total of 35 publications were obtained by searching the PubMed, ScienceDirect, Chinese Web of knowledge (CNKI) and Wanfang databases. A total of 12,354 horses were assessed, of which 1580 were positive for T. gondii. The pooled overall seroprevalence of horses infected by T. gondii was 11.29%. No significant difference of T. gondii seroprevalence was observed between male and female horses. The seroprevalence of T. gondii in horses from different countries varied. Our findings suggest that toxoplasmosis is prevalent in horses worldwide. Therefore, it is necessary to implement continuous monitoring of the status of T. gondii seroprevalence in horses. Moreover, powerful regulatory measures should be implemented to prevent and control the spread of toxoplasmosis.

Keywords: Horse; Meta-analysis; Seroprevalence; Toxoplasmosis; Zoonosis.

Publication types

  • Meta-Analysis
  • Systematic Review

MeSH terms

  • Animals
  • Female
  • Horses / parasitology*
  • Humans
  • Male
  • Prevalence
  • Seroepidemiologic Studies
  • Toxoplasmosis, Animal / epidemiology*
  • Zoonoses / epidemiology*