Oral mucosal reactions to cinnamon-flavored chewing gum

J Am Dent Assoc. 1988 May;116(6):664-7. doi: 10.14219/jada.archive.1988.0003.


Oral lesions induced by contact with cinnamon flavoring agents are relatively uncommon, and are probably unrecognized as such by many clinicians. Ten patients with these lesions seen during the past 6 years are described in this report. Most patients had a "burning sensation" as their primary symptom. Clinically, lesions appeared as erythematous patches with varying degrees of superimposed keratosis or ulceration, or both. The lesions were usually confined to the buccal mucosa and lateral border of the tongue. The offending agent was almost always cinnamon-flavored chewing gum, and symptoms typically resolved within 1 to 2 days of discontinuing the product containing cinnamon.

MeSH terms

  • Adult
  • Aged
  • Chewing Gum / adverse effects*
  • Cinnamomum zeylanicum / adverse effects*
  • Condiments / adverse effects*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mouth Mucosa / drug effects
  • Mouth Mucosa / pathology
  • Stomatitis / chemically induced*
  • Stomatitis / pathology
  • Ulcer / chemically induced
  • Ulcer / pathology


  • Chewing Gum