Review
Aloe Vera
In: LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012.
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- PMID: 31643946
- Bookshelf ID: NBK548634
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Review
Aloe Vera
Excerpt
Aloe vera is a cactus-like plant belonging to the Lily family, extracts of which are used topically for skin care and orally as a component of many herbal mixtures claimed to have medicinal benefits. Oral forms of aloe vera have been linked to rare instances of clinically apparent liver injury.
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References
CITED REFERENCES
References
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- Zimmerman HJ. Unconventional drugs. Miscellaneous drugs and diagnostic chemicals. In, Zimmerman, HJ. Hepatotoxicity: the adverse effects of drugs and other chemicals on the liver. 2nd ed. Philadelphia: Lippincott,1999: pp. 731-4.(Expert review of hepatotoxicity published in 1999; several herbal medications are discussed, but not aloe vera).
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- Liu LU, Schiano TD. Hepatotoxicity of herbal medicines, vitamins and natural hepatotoxins. In, Kaplowitz N, DeLeve LD, eds. Drug-induced liver disease. 2nd ed. New York: Informa Healthcare USA, 2007, pp. 733-54.(Review of hepatotoxicity of herbal and dietary supplements [HDS] published in 2007; mentions that aloe vera is generally nonhepatotoxic).
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- Aloe. In, PDR for Herbal Medicines. 4th ed. Montvale, New Jersey: Thomson Healthcare Inc. 2007: pp. 19-26.(Compilation of short monographs on herbal medications and dietary supplements).
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- Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract. 1999;49:823–8. [ (Systematic review of the literature on aloe vera identified 3 controlled trials of oral therapy for short periods in hyperlipidemia and diabetes found only mild and reversible adverse events and no mention of hepatotoxicity). ] - PMC - PubMed
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- Stedman C. Herbal hepatotoxicity. Semin Liver Dis. 2002;22:195–206. [ (Review and description of patterns of liver injury due to herbals, including discussion of potential risk factors, and herb-drug interactions). ] - PubMed
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