Pill-induced esophagitis caused by ingesting excessive caffeine tablets

Clin J Gastroenterol. 2020 Jun;13(3):334-339. doi: 10.1007/s12328-019-01055-w. Epub 2019 Oct 23.

Abstract

A 19-year-old woman with suicidal thoughts consumed 24 anhydrous caffeine tablets and was admitted to our hospital. After being discharged from the hospital, her oral intake remained impaired because of retrosternal pain and she was readmitted. An upper gastrointestinal endoscopy revealed diffuse ulcers throughout the mid-to-lower esophagus; the patient was diagnosed with caffeine-induced esophagitis. She recovered soon after conservative treatment. A follow-up endoscopy performed 1 month after the patient was discharged showed that the ulcers had healed. This case highlights the risk of esophageal injuries after ingesting excessive caffeine tablets, which were sold as dietary supplement without a prescription. Our experience indicates that endoscopic surveillance is advisable to prevent severe complications if a patient presents with esophageal symptoms suggestive of chemical esophagitis.

Keywords: Caffeine overdose; Diffuse ulcer; Gastrointestinal endoscopy; Pill-induced esophagitis.

Publication types

  • Case Reports

MeSH terms

  • Caffeine / administration & dosage
  • Caffeine / adverse effects
  • Esophagitis / diagnostic imaging
  • Esophagitis / etiology*
  • Esophagoscopy
  • Esophagus / diagnostic imaging
  • Esophagus / injuries
  • Female
  • Humans
  • Tablets / adverse effects*
  • Tomography, X-Ray Computed
  • Young Adult

Substances

  • Tablets
  • Caffeine