1 Division of Genetics, Departments of Medicine and Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA. Electronic address: pacole@bwh.harvard.edu.
2 Department of Biology and Biotechnology, University of Pavia, Via Ferrata 1, 27100 Pavia, Italy. Electronic address: andrea.mattevi@unipv.it.