Two cases of oral pigmentation associated with quinidine therapy

Oral Surg Oral Med Oral Pathol. 1988 Jul;66(1):59-61. doi: 10.1016/0030-4220(88)90067-9.


Melanin pigmentation of the hard palate is described in two patients receiving long-term quinidine therapy for cardiac arrhythmia. The importance of quinidine-induced oral pigmentation in the differential diagnosis of oral pigmentary disturbances is discussed.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Female
  • Humans
  • Male
  • Melanins
  • Middle Aged
  • Mouth Diseases / chemically induced
  • Mouth Mucosa / drug effects*
  • Palate*
  • Pigmentation Disorders / chemically induced*
  • Quinidine / adverse effects*


  • Melanins
  • Quinidine